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KMID : 1123920220360020054
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Korean Journal of Oriental Physiology and Pathology
2022 Volume.36 No. 2 p.54 ~ p.58
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Experimental Effects of Aucklandiae Radix and Cyperi Rhizoma Extract on Chronic Stress in Rats
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Choi Chan-Hun
Hong Jun-Yeong
Jeong Hyun-Woo
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Abstract
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This study aimed to investigate the anti-stress function of Aucklandiae Radix (AR) and Cyperi Rhizoma (CR). The essential oils used in the experiment were extracted from AR and CR using Steam Distillation Extraction and Super critical CO2 extraction. To observe the effects of sample administration, we measured feed intake, leukocytes, red blood cells, hemoglobin, platelets, serum serotonin content, immobility time, climbing time, and swimming time in mice subjected to chronic restraint stress as behavioral changes. The average body weight of all experimental groups increased than the average body weight of the control group. The immobility and climbing times of experimental groups A and B administered with supercritical extraction samples were shorter than those of the other experimental groups and the control group, and the swimming time was longer. The serotonin content in the blood of all experimental groups decreased compared to the normal group, and the serotonin content of the control group was increased. The authors suggest that Korean herbal medicines AR and CR may be utilized as anti-stress flavoring agents based on the above results.
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KEYWORD
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Aucklandiae Radix, Cyperi Rhizoma, chronic restraint stresse, Steam Distillation Extraction, Super critical CO2 extraction, flavoring
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